Top 7 Best Medicines For Dog Paw Licking

James Vega | 25-02-2026

Constant paw licking in dogs is often a sign of allergies, irritation, or underlying skin issues. Left untreated, this behavior can lead to discomfort, hot spots, and even infections, making it important for pet owners to address the root cause quickly and safely.

This guide reviews the most effective medicines and treatments for dog paw licking, including allergy chews, topical sprays, and ointments. You’ll find clear comparisons, practical pros and cons, and advice to help you choose the right solution for your dog’s needs.

Editor's Choice
Veterinary Formula Hot Spot & Itch Relief Spray
Veterinary Formula Hot Spot & Itch Relief Spray
Premium Pick
Zesty Paws Allergy Relief Chews Immune & Skin
Zesty Paws Allergy Relief Chews Immune & Skin
Budget Pick
Sulfodene Dog Wound Care 3-Way Ointment
Sulfodene Dog Wound Care 3-Way Ointment

Top 7 Best Medicines For Dog Paw Licking

After reviewing and comparing the most popular Best Medicines For Dog Paw Licking options, we identified the products that offer the best balance of quality, performance, and value.

1. TTLXRL Dog Allergy Chews 200ct

Best for Multi-Dog Households
TTLXRL Dog Allergy Chews 200ct

Dogs suffering from persistent paw licking, itching, or skin irritation often need ongoing support for allergies and immune health. Chewable supplements like these can make daily care easier, especially when managing symptoms across multiple pets.

TTLXRL Dog Allergy Chews stand out for their generous 200-count supply, making them a practical choice for families with more than one dog or for those seeking a long-lasting solution. The formula supports skin, gut, and immune health, and is gentle enough for dogs of all ages and sizes.

  • Large 200-count jar: Offers extended use and value for homes with several dogs
  • Natural, hypoallergenic ingredients: Includes salmon oil, colostrum, and probiotics for gentle relief
  • Flexible dosing: Suitable for small and large breeds, with easy-to-follow instructions

Compared to smaller packs or single-dog formulas, TTLXRL prioritizes cost-effectiveness and convenience. The main tradeoff is that the chews may take time to show results, especially for severe cases.

Strength
  • Large supply for multiple dogs
  • Natural, grain-free formula
  • Supports immune and digestive health
  • Flexible dosing for all sizes
  • Chicken flavor appeals to most dogs
Weakness
  • Results may take time
  • Not a topical solution

2. Sulfodene Dog Wound Care 3-Way Ointment

Best for Infection Prevention
Sulfodene Dog Wound Care 3-Way Ointment
9.5

Sulfodene

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Open sores or raw skin from excessive paw licking can quickly become infected if not properly treated. A topical ointment is essential for managing minor wounds and preventing complications.

Sulfodene Dog Wound Care 3-Way Ointment is designed to relieve pain, block germs, and support healing for cuts, scrapes, and skin irritation. It's a practical addition to any pet first aid kit, especially for dogs prone to licking or scratching their paws.

  • Triple-action formula: Relieves pain, prevents infection, and protects against germs
  • Barrier protection: Shields wounds from flies and bacteria
  • Affordable and effective: Suitable for everyday wound care needs

Unlike oral supplements, this ointment provides immediate topical relief and protection. However, it is not intended for deep wounds or as a long-term allergy solution.

Strength
  • Helps prevent infection
  • Relieves pain on contact
  • Easy topical application
  • Affordable for regular use
  • Trusted brand for wound care
Weakness
  • For external use only
  • Not for deep wounds

3. Veterinary Formula Hot Spot & Itch Relief Spray

Best Everyday Relief Formula
Veterinary Formula Hot Spot & Itch Relief Spray
9.8

Veterinary Formula

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Frequent paw licking and scratching often require fast, on-the-spot relief to break the itch cycle. Sprays are a convenient way to soothe irritated skin between baths or after walks.

Veterinary Formula Hot Spot & Itch Relief Spray offers a gentle, non-irritating formula suitable for both dogs and cats. It's ideal for pet owners looking for a quick, affordable way to calm hot spots, insect bites, or allergy-related itching.

  • Moisturizing ingredients: Wheat germ oil and other actives soothe and hydrate skin
  • Paraben and dye-free: Safe for regular use on sensitive pets
  • Works between washes: Complements shampoo routines for ongoing care

Compared to ointments or chews, this spray is easy to apply and provides immediate comfort. The main tradeoff is that it may need to be reapplied for persistent or severe cases.

Strength
  • Quick topical relief
  • Safe for dogs and cats
  • Non-irritating formula
  • Affordable option
  • Moisturizes skin
Weakness
  • Requires frequent reapplication
  • Not a long-term allergy fix

4. Zesty Paws Allergy Relief Chews Immune & Skin

Best for Immune and Skin Support
Zesty Paws Allergy Relief Chews Immune & Skin
9.8

Zesty Paws

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Dogs with chronic paw licking often benefit from a supplement that addresses both immune health and skin comfort. Chews are a popular choice for ongoing, daily support.

Zesty Paws Allergy Relief Chews combine probiotics, colostrum, and Omega-3s to target itchy skin and promote a healthy immune response. They're especially suitable for dogs with recurring seasonal or environmental allergies.

  • EpiCor Pets ingredient: Supports immune function for better allergy resistance
  • Colostrum and Astragalus Root: Help maintain normal histamine levels and skin comfort
  • Added probiotics: Promote gut health, which is linked to allergy symptoms

Compared to sprays or ointments, these chews provide internal support and are easy to give daily. The main tradeoff is that they may not offer immediate relief for acute flare-ups.

Strength
  • Targets immune and skin health
  • Contains probiotics for gut support
  • Easy daily chew format
  • Suitable for most dogs
  • Includes Omega-3 fatty acids
Weakness
  • Not a topical solution
  • May take time for effects

5. Veterinary Formula Clinical Care Medicated Spray

Best for Skin Health Support
Veterinary Formula Clinical Care Medicated Spray
9.1

Veterinary Formula

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Persistent paw licking can lead to red, scaly, or greasy skin that needs targeted care. Medicated sprays are useful for supporting skin recovery and comfort between baths.

Veterinary Formula Clinical Care Medicated Spray is formulated to soothe and moisturize irritated skin, making it a good choice for dogs with ongoing skin health challenges. It's also suitable for cats, offering versatility for multi-pet households.

  • Supports healthy skin: Moisturizes and calms red or greasy areas
  • Paraben-free and non-irritating: Gentle enough for regular use
  • Pleasant scent: Helps with routine application

This spray prioritizes skin health and ease of use compared to oral supplements. The tradeoff is that it works best as part of a broader care routine, not as a standalone allergy solution.

Strength
  • Soothes red or greasy skin
  • Safe for dogs and cats
  • Non-irritating formula
  • Pleasant scent
  • Affordable
Weakness
  • Works best with shampoo routine
  • Not a cure for allergies

6. Zesty Paws Allergy Relief Chews Peanut Butter

Best Flavor Variety Option
Zesty Paws Allergy Relief Chews Peanut Butter
9.1

Zesty Paws

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Some dogs are picky eaters, making it hard to administer supplements for paw licking and allergies. Chews with appealing flavors can make daily routines easier and more enjoyable for both pets and owners.

Zesty Paws Allergy Relief Chews in Peanut Butter flavor offer the same immune and skin support as the original formula, but with a taste that many dogs love. They're ideal for dogs who resist other flavors or need a little extra encouragement.

  • Peanut butter flavor: Appeals to picky or sensitive dogs
  • Immune and skin support: Includes EpiCor Pets, colostrum, and Omega-3s
  • Probiotics for gut health: Supports overall wellness

Compared to standard-flavored chews, this option prioritizes palatability. The main tradeoff is that flavor preferences can vary, so not all dogs will respond the same.

Strength
  • Peanut butter flavor
  • Supports immune and skin health
  • Contains probiotics
  • Easy to administer
  • Suitable for daily use
Weakness
  • Flavor may not suit all dogs
  • Not a topical solution

7. GOODGROWLIES Dog Allergy Relief Chews

Best Chewable Allergy Support
GOODGROWLIES Dog Allergy Relief Chews
8

Goodgrowlies

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Dogs with seasonal allergies and chronic paw licking often need a supplement that is easy to give and offers broad support. Chewable formats are especially helpful for dogs that dislike pills or topical treatments.

GOODGROWLIES Dog Allergy Relief Chews provide a blend of natural antihistamines, fish oil, turmeric, and quercetin for comprehensive allergy and itch relief. They're suitable for all breeds and come with a satisfaction guarantee for added peace of mind.

  • Chewable format: Makes daily administration simple and stress-free
  • Advanced formula: Combines natural ingredients for multi-symptom relief
  • Vet-approved and made in the USA: Ensures quality and safety

Compared to sprays or ointments, these chews focus on internal support and ease of use. The tradeoff is that they may not provide immediate relief for acute symptoms.

Strength
  • Easy chewable format
  • Natural antihistamine blend
  • Fish oil and turmeric included
  • Suitable for all breeds
  • Vet-approved
Weakness
  • May require regular use for results
  • Not for immediate symptom relief

Buying Guide: How to Choose the Best Medicines for Dog Paw Licking

Medicines for dog paw licking range from chewable supplements to sprays and ointments, each addressing different causes and symptoms. Choosing the right solution means understanding your dog's specific needs, the root cause of their licking, and how each product type works. Many buyers assume all paw licking is due to allergies, but it can also stem from infections, yeast, or behavioral issues—so matching the product to the problem is key.

Choosing Between Chews, Sprays, and Ointments

The main decision is whether your dog needs ongoing internal support (chews), fast topical relief (sprays), or wound protection (ointments). Chews are best for dogs with chronic allergies or skin sensitivities, while sprays and ointments are useful for acute flare-ups or open sores.

Considering Pack Size and Value

If you have multiple dogs or need long-term support, larger packs like TTLXRL or BuddyCheer offer better value and less frequent repurchasing. For occasional or single-dog use, smaller packs or sprays may be more practical.

Addressing Flavor and Palatability

Dogs that resist supplements may respond better to flavored chews, such as Zesty Paws Peanut Butter. If your dog is especially picky, consider trying a small pack first to ensure acceptance.

Matching Product to Symptom Severity

For mild to moderate paw licking, sprays or flavored chews may be enough. For severe cases with open wounds or persistent infection, a combination of ointment and internal support may be needed. Always consult your veterinarian if symptoms persist or worsen.

Final Buying Advice

Choosing the right medicine for dog paw licking depends on your dog's symptoms, preferences, and your household's needs. Start with the mildest, most appropriate solution and monitor results before moving to more intensive options.

FAQ For Medicines For Dog Paw Licking

1. What causes dogs to lick their paws excessively?

Common causes include allergies (environmental or food), skin irritation, yeast or bacterial infections, and sometimes behavioral issues. Identifying the root cause is important for effective treatment.

2. Are chewable supplements or sprays better for paw licking?

Chewable supplements are best for ongoing allergy or immune support, while sprays provide quick, topical relief for itching. The right choice depends on your dog's needs and symptom severity.

3. How long does it take for allergy chews to work?

Most allergy chews require consistent daily use for 2–4 weeks to show noticeable improvement. Results may vary depending on the dog's condition and the product used.

4. Can I use multiple products together?

Yes, many owners use a combination of chews for internal support and sprays or ointments for immediate relief. Always follow dosing instructions and consult your veterinarian if unsure.

5. Are these products safe for all dog breeds and ages?

Most products reviewed are suitable for all breeds and ages, but always check the label for age or weight restrictions. Consult your vet before starting new supplements, especially for puppies or senior dogs.

6. When should I see a veterinarian for paw licking?

If your dog's licking is severe, causes open wounds, or doesn't improve with over-the-counter solutions, consult your veterinarian. Persistent symptoms may indicate a more serious underlying issue.

James Vega

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