Best Dentastix Medium Dog: Top Picks

James Vega | 10-02-2026

Dental health is a common concern for dog owners, especially when it comes to medium breeds that are prone to tartar buildup and bad breath. Finding a treat that not only satisfies your dog’s cravings but also supports their oral hygiene can be challenging, with so many options promising similar results.

This guide compares the leading Dentastix and dental chew options for medium dogs, focusing on pack size, flavor variety, and ingredient quality. Whether you’re looking for a bulk buy, a gluten-free alternative, or a treat with a softer texture, you’ll find clear, practical recommendations to help you choose the right dental treat for your dog’s daily routine.

Editor's Choice
Pedigree Dentastix Small & Medium Dog Treats Chicken 45 Count
Pedigree Dentastix Small & Medium Dog Treats Chicken 45 Count
Premium Pick
Pedigree Dentastix Small & Medium Chicken 25 Count
Pedigree Dentastix Small & Medium Chicken 25 Count
Budget Pick
Pedigree Dentastix Large Breed Fresh Flavor Treats
Pedigree Dentastix Large Breed Fresh Flavor Treats

Top 7 Best Dentastix Medium Dog

After reviewing and comparing the most popular Best Dentastix Medium Dog options, we identified the products that offer the best balance of quality, performance, and value.

1. Pedigree Dentastix Small & Medium Dog Treats Chicken 45 Count

Best Large Count for Medium Dogs
Pedigree Dentastix Small & Medium Dog Treats Chicken 45 Count
9.8

Pedigree

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Oral health is a daily concern for dog owners, and dental treats like these help reduce tartar and freshen breath in medium breeds. Regular use supports a cleaner mouth and can make dental care less stressful for both you and your dog.

This 45-count pack from Pedigree is ideal for households with one or more medium dogs, offering a generous supply and a flavor most dogs enjoy. It's best suited for owners seeking a reliable, straightforward dental treat with a proven formula.

  • Large 45-count pack provides extended value for medium dog owners
  • Triple-action formula helps reduce tartar, clean teeth, and freshen breath
  • No added sugar or fillers for a cleaner ingredient list

Compared to smaller packs or specialty flavors, this option prioritizes quantity and everyday convenience. The main tradeoff is less variety in flavor, but the chicken taste is widely accepted by most dogs.

Strength
  • Large pack size
  • Triple-action dental care
  • No added sugar
  • Popular chicken flavor
  • Chewy X-shape design
Weakness
  • Single flavor only
  • Bulk pack may not suit all budgets

2. Pedigree Dentastix Large Breed Fresh Flavor Treats

Best Fresh Flavor for Large Dogs
Pedigree Dentastix Large Breed Fresh Flavor Treats
9.1

Pedigree

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Maintaining oral hygiene in large dogs can be a challenge, especially if they are picky about flavors. Dental treats designed for larger breeds help clean teeth and control tartar in a way that's easy to incorporate into daily routines.

This fresh-flavored Dentastix is tailored for large dogs, offering a taste that helps freshen breath while supporting dental health. It's a strong choice for owners of bigger breeds who want a treat that's both effective and appealing.

  • Fresh flavor helps improve breath and appeal to dogs
  • X-shape and chewy texture designed to clean hard-to-reach teeth
  • No added sugar or fillers for a straightforward recipe

Unlike chicken or beef options, this treat focuses on breath-freshening and is sized for large dogs. The tradeoff is that it's not ideal for smaller breeds or those needing more flavor variety.

Strength
  • Fresh flavor for breath
  • Sized for large dogs
  • Triple-action cleaning
  • No added sugar
Weakness
  • Not for medium or small dogs
  • Limited flavor selection

3. Pedigree Dentastix Small & Medium Chicken 25 Count

Best Compact Pack for Medium Dogs
Pedigree Dentastix Small & Medium Chicken 25 Count
9.5

Pedigree

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For dog owners who want to try dental treats without committing to a large pack, a compact option can be more practical and budget-friendly. Dental treats are important for maintaining oral health between vet visits, especially for medium breeds.

This 25-count pack offers the same triple-action benefits as larger packs but in a more manageable size. It's well-suited for new users, smaller households, or those who prefer to buy treats more frequently for freshness.

  • Compact 25-count pack ideal for trial or smaller households
  • Triple-action dental care supports daily oral hygiene
  • No added sugar or fillers for peace of mind

Compared to bulk options, this pack is easier to store and finish before treats go stale. The tradeoff is a higher cost per treat and fewer treats per purchase.

Strength
  • Smaller pack size
  • Triple-action formula
  • No added sugar
  • Chewy X-shape design
Weakness
  • Higher cost per treat
  • Single flavor only

4. Pedigree Dentastix Large Breed Beef Flavor 40 Count

Best Beef Flavor Option
Pedigree Dentastix Large Breed Beef Flavor 40 Count
9.1

Pedigree

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Some dogs prefer beef over chicken or fresh flavors, making it important to have a dental treat that matches their taste. Dental chews like these help maintain oral health in large breeds while providing a flavor they love.

This 40-count beef-flavored pack is best for large dog owners looking for a change from standard chicken options. It delivers the same cleaning benefits with a taste that appeals to beef-loving dogs.

  • Beef flavor offers variety for picky eaters
  • 40-count pack provides a good supply for large breeds
  • No added sugar or fillers for a simple ingredient list

Compared to chicken or fresh flavors, this option prioritizes taste variety for large dogs. The main tradeoff is that it’s not suitable for smaller breeds.

Strength
  • Beef flavor variety
  • Large pack size
  • Triple-action dental care
  • No added sugar
Weakness
  • Not for small or medium dogs
  • Single flavor per pack

5. Pedigree Dentastix 65 Piece Variety Pack

Best Multi-Flavor Variety Pack
Pedigree Dentastix 65 Piece Variety Pack
8.9

Pedigree

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Dogs can get bored with the same treat every day, and a variety pack helps keep things interesting while supporting dental health. Rotating flavors may also help with picky eaters or multiple dogs with different preferences.

This 65-piece pack includes original, fresh, and beef flavors, making it a versatile choice for households with more than one dog or those who want to add variety to their dog's routine. It's best for owners who value both quantity and flavor options.

  • Three flavors included for greater variety
  • Large 65-piece count covers multiple dogs or longer periods
  • Clinically proven to reduce tartar for peace of mind

Compared to single-flavor packs, this option prioritizes variety and flexibility. The tradeoff is that not every dog may like every flavor included.

Strength
  • Multiple flavors in one pack
  • Large quantity
  • Clinically proven formula
  • Good for multi-dog homes
Weakness
  • Not all dogs like every flavor
  • Bulk pack may be too large for some

6. Pedigree Dentastix Small & Toy Fresh 102 Count

Best Bulk Option for Small Dogs
Pedigree Dentastix Small & Toy Fresh 102 Count
8.7

Pedigree

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Owners of small or toy breeds often need a dental treat that fits their dog's size and lasts through frequent use. Bulk packs can be more cost-effective and convenient for daily routines.

This 102-count fresh flavor pack is designed for small and toy breeds, offering a long-lasting supply and a formula that helps reduce tartar and freshen breath. It's ideal for owners looking to stock up and simplify their treat-buying routine.

  • Bulk 102-count pack for extended use
  • Fresh flavor helps with breath and appeal
  • No added sugar or fillers for ingredient-conscious buyers

Compared to smaller packs, this bulk option prioritizes convenience and value for small dog owners. The tradeoff is that it’s not suitable for larger breeds.

Strength
  • Very large pack size
  • Fresh flavor
  • Triple-action cleaning
  • No added sugar
Weakness
  • Not for medium or large dogs
  • May go stale if not used quickly

7. Dentalife Daily Oral Care Dog Treats Chicken

Best VOHC-Approved Alternative
Dentalife Daily Oral Care Dog Treats Chicken
7.9

Dentalife

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Some owners prefer dental treats with third-party approval for effectiveness. VOHC-approved chews are recognized for their ability to help reduce tartar and support oral health in dogs.

Dentalife's chicken-flavored chews offer a unique texture and a VOHC seal, making them a strong alternative to standard Dentastix. They're best for buyers who want added assurance of dental benefits and a different texture for their dog.

  • VOHC-approved for clinically proven tartar reduction
  • Unique 8-ridge design helps clean hard-to-reach teeth
  • No wheat, corn, or soy for sensitive dogs

Compared to traditional Dentastix, this option prioritizes clinical validation and ingredient simplicity. The tradeoff is a different texture and flavor profile that may not suit every dog.

Strength
  • VOHC-approved formula
  • No wheat, corn, or soy
  • Unique cleaning texture
  • Resealable pack
Weakness
  • Different texture than Dentastix
  • Flavor variety limited

Buying Guide: How to Choose the Best Dental Treats for Medium Dogs

Dental treats are a practical tool for supporting your dog's oral health, but not all chews are created equal. Buyers face tradeoffs between pack size, flavor, ingredient quality, and the specific needs of their dog's breed or sensitivities. It's easy to assume all dental treats work the same, but differences in texture, approval standards, and formula can have a real impact on both effectiveness and enjoyment for your pet.

Choosing the Right Pack Size for Your Dog

Pack size is more than just a matter of cost—it's about freshness and convenience. Bulk packs work well for multi-dog homes or daily treat routines, while smaller packs are better for occasional use or trying new flavors. Consider how quickly your dog goes through treats and whether you have storage space to keep them fresh.

Flavor and Texture Preferences

Dogs can be picky, and rotating flavors or switching textures can help maintain interest in dental care. Variety packs or dual-flavor options are great for households with multiple dogs or those who tire of the same treat. Chewy options are ideal for sensitive mouths or older dogs, while standard sticks and ridged chews provide more lasting engagement for strong chewers.

Ingredient Sensitivities and Special Diets

If your dog has allergies or food sensitivities, look for treats labeled gluten-free or free from common fillers like wheat, corn, or soy. Some brands also avoid added sugars or artificial ingredients, which can be important for health-conscious owners.

Clinical Validation and Effectiveness

VOHC-approved treats are tested for their ability to reduce tartar, offering extra peace of mind. If clinical validation is important to you, seek out products with this certification. However, many non-approved treats still provide real-world benefits when used consistently as part of a dental care routine.

Matching Treat Size to Your Dog

Always choose a treat size appropriate for your dog's weight and breed. Using treats intended for larger dogs on smaller breeds can increase the risk of choking, while undersized treats may not provide enough cleaning action for bigger dogs.

Final Buying Advice

Choosing the right dental treat for your medium dog comes down to matching your dog's chewing habits, dietary needs, and your household's routine. Don't assume one product fits all—consider pack size, flavor, texture, and ingredient sensitivities before buying.

FAQ For Dentastix Medium Dog

1. How often should I give my dog dental treats?

Most dental treats are designed for daily use. Always follow the feeding guidelines on the package and consult your vet for your dog's specific needs.

2. Are Dentastix safe for all dog breeds?

Dentastix are generally safe when given in the correct size for your dog's breed and weight. Always supervise your dog while chewing and choose the appropriate product.

3. Do dental treats replace brushing my dog's teeth?

Dental treats help reduce tartar and freshen breath but do not replace regular brushing or professional dental care. Use them as part of a complete oral hygiene routine.

4. What should I do if my dog has food allergies?

Choose treats labeled gluten-free or free from common allergens like wheat, corn, or soy. Always check the ingredient list and consult your vet if unsure.

5. How do I store dental treats to keep them fresh?

Store treats in a cool, dry place and reseal the package after each use. Bulk packs may be divided into smaller containers to maintain freshness.

6. Are VOHC-approved treats better than regular dental chews?

VOHC-approved treats have been tested for effectiveness in reducing tartar, offering extra assurance. However, many non-approved treats still provide real benefits when used consistently.

James Vega

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