Best Pedigree Dentastix Medium Dog: Top Picks

James Vega | 22-02-2026

Keeping your dog’s teeth clean can be a daily challenge, especially for medium breeds prone to tartar and plaque buildup. Many owners struggle to find treats that both satisfy their dog’s chewing instincts and genuinely support dental health without added sugars or fillers.

This guide reviews the leading Pedigree Dentastix options for medium dogs, highlighting differences in pack size, flavor, and texture. You’ll find practical advice for choosing the right dental treat based on your dog’s needs, as well as clear comparisons to help you make a confident, informed choice.

Editor's Choice
Pedigree Dentastix Small & Medium Dog Treats Chicken 45 Count
Pedigree Dentastix Small & Medium Dog Treats Chicken 45 Count
Premium Pick
Pedigree Dentastix Small & Medium Chicken 25 Count
Pedigree Dentastix Small & Medium Chicken 25 Count
Budget Pick
Pedigree Dentastix Large Breed Variety Pack
Pedigree Dentastix Large Breed Variety Pack

Top 7 Best Pedigree Dentastix Medium Dog

After reviewing and comparing the most popular Best Pedigree Dentastix Medium Dog options, we identified the products that offer the best balance of quality, performance, and value.

1. Pedigree Dentastix Small & Medium Dog Treats Chicken 45 Count

Best Large Count for Medium Dogs
Pedigree Dentastix Small & Medium Dog Treats Chicken 45 Count
9.8

Pedigree

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Dental health is a common concern for medium dogs, as tartar and plaque can quickly accumulate without regular care. Dental treats like these offer a convenient way to support oral hygiene while giving your dog a daily reward.

This 45-count pack is ideal for owners who want a longer-lasting supply, reducing the need for frequent repurchasing. It's best suited for medium dogs (22-40 lbs.) who enjoy a chicken flavor and benefit from daily dental support.

  • Large 45-count pack: Provides over a month of daily treats for medium dogs
  • Triple action formula: Reduces tartar, cleans teeth, and freshens breath
  • No added sugar or fillers: Supports a cleaner ingredient list for daily use

Compared to smaller packs, this option prioritizes value and convenience for medium dog owners. The main tradeoff is a larger upfront purchase, but it minimizes the hassle of running out.

Strength
  • Large pack size
  • Triple action dental care
  • No added sugar
  • Popular chicken flavor
  • Ideal for daily use
Weakness
  • Higher upfront cost
  • Not suited for small or large breeds

2. Pedigree Dentastix Small & Medium Chicken 25 Count

Best Compact Pack for Medium Dogs
Pedigree Dentastix Small & Medium Chicken 25 Count
9.5

Pedigree

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For owners who want to try dental treats without a big commitment, a smaller pack can be a practical starting point. Dental care is still essential, but not everyone needs or wants a bulk supply.

This 25-count pack is well-suited for medium dogs or households with limited storage. It's a good fit for those looking to test flavor or incorporate treats into a rotation.

  • Compact 25-count pack: Easier to store and finish before expiration
  • Triple action cleaning: Helps reduce tartar and freshen breath
  • No added sugar or fillers: Keeps ingredients simple for everyday use

Compared to larger packs, this option prioritizes flexibility and freshness. The tradeoff is a higher cost per treat, but it reduces waste and storage needs.

Strength
  • Convenient pack size
  • Supports dental health
  • No fillers
  • Easy to store
Weakness
  • Fewer treats per pack
  • Higher cost per treat

3. Pedigree Dentastix Large Breed Fresh Flavor

Best Fresh Flavor for Large Dogs
Pedigree Dentastix Large Breed Fresh Flavor
9.1

Pedigree

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Large breed dogs often require treats that can handle their stronger jaws and larger teeth, making dental care even more important. Dental treats designed for bigger dogs help ensure effective cleaning and satisfaction.

This fresh flavor treat is tailored for large breeds, offering a taste alternative to traditional chicken. It's best for owners looking to add variety or address breath concerns in bigger dogs.

  • Fresh flavor option: Appeals to dogs who prefer minty or clean tastes
  • Large breed sizing: Sized appropriately for dogs 40 lbs. and up
  • Triple action formula: Reduces tartar, cleans teeth, and freshens breath

Compared to small or medium dog treats, this product prioritizes flavor variety and size. The tradeoff is that it's not suitable for smaller dogs.

Strength
  • Fresh flavor alternative
  • Sized for large dogs
  • Triple action dental care
  • No added sugar
Weakness
  • Not for medium or small dogs
  • Limited flavor options

4. Pedigree Dentastix Large Breed Variety Pack

Best Flavor Variety for Large Dogs
Pedigree Dentastix Large Breed Variety Pack
9.5

Pedigree

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Keeping large dogs interested in daily dental care can be challenging if they tire of the same flavor. A variety pack helps maintain enthusiasm while still supporting oral hygiene.

This pack offers three different flavors, making it ideal for large breed owners who want to keep treat time exciting. It's best for multi-dog households or picky eaters.

  • Three flavor options: Includes Original, Beef, and Fresh for variety
  • Large breed formulation: Designed for dogs 40 lbs. and above
  • No added sugar or fillers: Maintains ingredient quality across flavors

Compared to single-flavor packs, this variety option prioritizes engagement and choice. The main tradeoff is that it’s only available for large breeds.

Strength
  • Multiple flavors in one pack
  • Great for large dogs
  • No added sugar
  • Supports daily dental care
Weakness
  • Not for smaller breeds
  • May run out of favorite flavor first

5. Pedigree Dentastix Small & Toy Fresh 102 Count

Best Bulk Option for Small Dogs
Pedigree Dentastix Small & Toy Fresh 102 Count
8.7

Pedigree

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Small and toy breeds need dental care just as much as larger dogs, but their treat size and quantity requirements differ. Bulk packs can help owners stay stocked up and reduce shopping trips.

This 102-count pack is designed for small dogs who enjoy fresh flavor and need daily dental support. It's best for multi-dog homes or those who want to buy in bulk.

  • Bulk 102-count pack: Lasts over three months for small dogs
  • Fresh flavor: Appeals to dogs who prefer a minty taste
  • No added sugar or fillers: Suitable for regular use

Compared to smaller packs, this option prioritizes long-term value and convenience. The tradeoff is a larger storage requirement and upfront cost.

Strength
  • Very large pack size
  • Fresh flavor
  • No added sugar
  • Ideal for small breeds
Weakness
  • Not suitable for medium or large dogs
  • Requires more storage space

6. Pedigree Dentastix Dual Flavor Large Breed Bacon & Chicken

Best Dual Flavor for Large Dogs
Pedigree Dentastix Dual Flavor Large Breed Bacon & Chicken
8.5

Pedigree

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Large breed dogs can be picky, especially when it comes to daily dental treats. Offering more than one flavor in a single treat can help keep them interested and make dental care less of a chore.

This dual-flavor option combines bacon and chicken, making it a strong choice for owners of large dogs who want to add excitement to their pet’s routine. It’s best for dogs over 40 lbs. who enjoy savory flavors.

  • Dual bacon and chicken flavor: Appeals to dogs who like variety
  • Large breed sizing: Formulated for bigger mouths and teeth
  • No added sugar or fillers: Maintains a simple ingredient profile

Compared to single-flavor treats, this product prioritizes taste variety in every bite. The tradeoff is that it’s not suitable for smaller dogs.

Strength
  • Two flavors in one treat
  • Formulated for large breeds
  • No added sugar
  • Supports daily dental care
Weakness
  • Not for medium or small dogs
  • Single pack size only

7. Pedigree Dentastix 65 Piece Variety Pack

Best Multi-Flavor Variety Pack
Pedigree Dentastix 65 Piece Variety Pack
8.9

Pedigree

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Dogs can quickly lose interest in repetitive treats, making variety packs a smart way to keep dental care engaging. This is especially helpful for homes with multiple dogs or picky eaters.

This 65-piece pack includes three different flavors, offering flexibility and ongoing interest. It's a good fit for owners who want to provide their dogs with different taste experiences while maintaining dental health.

  • Includes three flavors: Original, Fresh, and Beef for rotation
  • 65-count pack: Suitable for extended use
  • Clinically proven to reduce tartar: Supports effective dental care

Compared to single-flavor or smaller packs, this option prioritizes variety and duration. The tradeoff is less specialization for a single breed size.

Strength
  • Multiple flavors included
  • Good pack size
  • Clinically proven formula
  • Suitable for multi-dog homes
Weakness
  • Not breed-size specific
  • May not suit all flavor preferences

Buying Guide: How to Choose the Best Dental Treats for Dogs

Dental treats are a practical way to support your dog's oral health, but not all options are created equal. Buyers must weigh factors like pack size, flavor, texture, and breed suitability. It's common to assume all dental treats work the same, but differences in design, approval, and ingredients can impact effectiveness and enjoyment.

Choosing the Right Pack Size

Pack size affects both cost and convenience. Bulk options are best for multi-dog homes or daily users, while smaller packs suit those testing new flavors or with limited storage.

Matching Treat Type to Dog Size

Dental treats are specifically formulated for small, medium, or large breeds. Using the correct size ensures safety and cleaning effectiveness.

Flavor and Texture Preferences

Dogs can be picky about flavors and textures. Some enjoy fresh or minty tastes, while others prefer chicken or beef. Texture also impacts dental benefit and enjoyment.

Ingredient Quality and Clinical Validation

Not all treats are created equal in terms of ingredients or clinical backing. Some buyers prioritize VOHC approval, while others focus on natural ingredients.

Final Buying Advice

Choosing the right dental treat comes down to your dog's size, preferences, and your own priorities for value and ingredient quality. Don't assume one treat fits all—match the product to your dog's specific needs for the best results.

FAQ For Pedigree Dentastix Medium Dog

1. How do I choose the right Dentastix size for my dog?

Select a treat formulated for your dog's weight range. Small and toy breeds need smaller treats, while medium and large breeds require larger, firmer options for safety and effectiveness.

2. Are Pedigree Dentastix safe for daily use?

Yes, when used as directed for your dog's size, Dentastix are designed for daily dental care. Always follow feeding guidelines and monitor your dog while chewing.

3. What is the difference between fresh and chicken flavors?

Fresh flavors offer a minty, clean taste that can help with breath, while chicken flavors appeal to dogs who prefer savory treats. Both support dental health.

4. Do dental treats replace brushing my dog's teeth?

Dental treats help reduce tartar and plaque but do not fully replace regular brushing. For best results, use treats alongside other dental care routines.

5. What does VOHC approval mean?

VOHC (Veterinary Oral Health Council) approval indicates that a dental treat meets standards for effectiveness in reducing tartar buildup, based on clinical testing.

6. Can I give Dentastix to puppies?

Dentastix are generally intended for adult dogs. Check the packaging for age recommendations and consult your veterinarian before giving dental treats to puppies.

7. How should I store bulk packs of dental treats?

Store treats in a cool, dry place and keep resealable packs closed to maintain freshness. Use treats before the expiration date to ensure quality.

James Vega

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